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:: Overview :: Precautions :: Side Effects Search results last updated: 9/17/2008

Generic & Brand Name : Source: (MedicineNet)

Brand Name : Xenical, alli
Generic Name : orlistat

Overview (Source: MedicineNet)
Orlistat is a drug that promotes loss of weight by preventing the digestion and absorption of fat in food. In the intestine, an enzyme called lipase (produced primarily by the pancreas) breaks apart fat in food so that it can be absorbed into the body. Orlistat blocks the action of lipase and thereby prevents the breakup and absorption of fat. Orlistat blocks absorption of about 25% of the fat in a meal. The unabsorbed fat is excreted in the stool. The FDA approved Orlistat by prescription in 1999. alli, a lower dose formulation of orlistat, was approved for purchase without a prescription "over the counter" in 2007. ...
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MedLinePlusWhy is this medication prescribed?
DrugDigestWhat is/are Xenical Capsules?
DrugInfoOnlinexenical

Precautions (Source: MedLinePlus)
Before taking orlistat, tell your doctor and pharmacist if you are allergic to orlistat or any other medications. talk to your doctor if you are taking medications that suppress the immune system such as cyclosporine (Neoral, Sandimmune). If you are taking cyclosporine (Neoral, Sandimmune), take it 2 hours before or 2 hours after orlistat. tell your doctor and pharmacist what prescription and nonprescription, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants (''blood thinners'') such as warfarin (Coumadin); medications for diabetes, such as glipizide (Glucotrol), glyburide (DiaBeta, Dynase, Micronase), metformin (Glucophage), and insulin; medications to control blood pressure; medications for thyroid disease; and any other medications for weight loss. tell your doctor if you have if you have had an organ transplant or if you have cholestasis (condition in which the flow of bile from the liver is blocked) or malabsorption syndrome (problems absorbing food). Your doctor will probably tell you not to take orlistat. tell your doctor if you have or have ever had an eating disorder such as anorexia nervosa or bulimia, diabetes,kidney stones, pancreatitis (inflammation or swelling of the pancreas), or gallbladder or thyroid disease. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Do not take orlistat if you are pregnant or breast-feeding. ...
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DrugDigest What should I watch for while using this medicine?

Side Effects (Source: MedLinePlus)
Orlistat may cause side effects. The most common side effect of orlistat is changes in bowel movement (BM) habits. This generally occurs during the first weeks of treatment; however, it may continue throughout your use of orlistat. Tell your doctor if any of these symptoms are severe or do not go away: oily spotting on underwear or on clothing; gas with oily spotting; urgent need to have a bowel movement; loose stools; oily or fatty stools; increased number of bowel movements; difficulty controlling bowel movements; pain or discomfort in the rectum (bottom); stomach pain; irregular menstrual periods; headache; anxiety. Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately: hives; rash; itching; difficulty breathing or swallowing; severe or continuous abdominal pain. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html ] or by phone [1-800-332-1088]. ...
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DrugDigest What side effects may I notice from this medicine?
DrugInfoOnline xenical

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