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:: Overview :: Precautions :: Side Effects :: Further Reading Search results last updated: 9/17/2008

Generic & Brand Name : Source: (RXList)

Brand Name : Xeloda
Generic Name : Capecitabine

Overview (Source: MedicineNet)
Capecitabine is an oral medication for treating advanced breast cancers that are resistant to combination therapy with the drugs of choice, paclitaxel (Taxol) and a drug from the anthracycline family of drugs, for example, doxorubicin (Adriamycin). Capecitabine is converted by the body to 5-fluorouracil (5-FU), a drug which has been given intravenously for many years to treat various types of cancer . It is not surprising, therefore, that capecitabine also is effective in the treatment of colorectal cancer, a type of cancer which is treated frequently with 5-FU. 5-FU inhibits the production of both DNA and protein by the cancerous cells that are necessary for the cells to divide and the cancer to grow in size. Capecitabine was approved by the FDA in 1998 for the treatment of breast cancer and in 2005 for the treatment of colorectal cancer. ...
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Precautions (Source: MedLinePlus)
Before taking capecitabine, tell your doctor and pharmacist if you are allergic to a capecitabine, fluorouracil, or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially those listed in the IMPORTANT WARNING section, antacids, folic acid, leucovorin, phenytoin (Dilantin), and vitamins. tell your doctor if you have or have ever had heart, liver, or kidney disease. women who are pregnant or breast-feeding should tell their doctors before they begin taking this drug. You should not plan to have children while receiving chemotherapy or for a while after treatments. (Talk to your doctor for further details.) Use a reliable method of birth control to prevent pregnancy. tell your doctor if you are breast-feeding. Capecitabine can cause serious side effects in nursing infants. do not have any vaccinations (e.g., measles or flu shots) without talking to your doctor. ...
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Side Effects (Source: MedLinePlus)
Side effects from capecitabine are common and include: diarrhea; nausea; vomiting; stomach pain; constipation; weakness; tiredness; dizziness; headache; sleeplessness; dry or itching skin; dehydration. If you experience any of the following symptoms or the one listed in the IMPORTANT WARNING section, call your doctor immediately: severe diarrhea (more than four bowel movements each day or diarrhea at night); decreased appetite (complete loss of appetite or only able to eat occasionally); severe vomiting (more than one time in a 24-hour period); tingling, numbness, pain, redness, or swelling of the hands or feet; sores or pain in the mouth or throat; fever or infection (a temperature of 100.5 degrees F or greater); chills; sore throat; chest pain; rash. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html ] or by phone [1-800-332-1088]. ...
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Further Reading on xeloda
  • Rectal Cancer ( WebMD )
    Rectal cancer is cancer of the rectum , the lower part of the colon that connects the large bowel to ...pain in the palms of the hands and the soles of the feet). Capecitabine ( Xeloda ): This drug is...

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