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:: Overview :: Precautions :: Side Effects :: Further Reading Search results last updated: 9/17/2008

Generic & Brand Name : Source: (RXList)

Brand Name : Welchol
Generic Name : Colesevelam Hcl

Overview (Source: MedicineNet)
Cholesterol made by the liver or from the food we eat can be converted into bile acids by the liver. The bile acids are secreted by the liver into the bile and enter the intestine with the bile. In the intestine the bile acids assist with the digestion of fat. Some of the bile acids are excreted from the body with the stool, but the majority of bile acids are absorbed from the intestine into the blood, are removed by the liver from the blood, and are re-secreted into the bile. Colesevelam binds bile acids in the intestine and causes more of the bile acids to be excreted in the stool. This reduces the amount of bile acids that returns to the liver and forces the liver to make more bile acids to replace the bile acids lost in the stool. In order to make more bile acids, the liver converts more cholesterol into bile acids, and this lowers the level of cholesterol in the blood. Colesevelam is not absorbed into the body. ...
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Precautions (Source: MedLinePlus)
Before taking colesevelam, tell your doctor and pharmacist if you are allergic to colesevelam or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially sustained-release formulations of verapamil (Calan SR) and vitamins and herbal products. tell your doctor if you have or have ever had gastrointestinal problems, especially bowel obstruction or difficulty swallowing foods, triglyceride levels greater than 300 mg/dl, bleeding problems, and low levels of fat-soluble vitamins (vitamins A, E, and K). tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking colesevelam, call your doctor. ...
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Side Effects (Source: MedLinePlus)
Side effects from colesevelam can occur. Tell your doctor if any of these symptoms are severe or do not go away: gas; constipation; upset stomach; headache; weakness; muscle pain; throat infection. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. ...
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Further Reading on welchol

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