Clinical experience with TALACEN has been insufficient to define all possible adverse reactions with this combination. However, reactions reported after oral administration of pentazocine hydrochloride in 50 mg dosage include gastrointestinal : nausea , vomiting, infrequently constipation ; and rarely abdominal distress, anorexia , diarrhea . CNS effects: dizziness , lightheadedness , hallucinations, sedation, euphoria , headache , confusion, disorientation; infrequently weakness, disturbed dreams , insomnia , syncope , visual blurring and focusing difficulty, depression ; and rarely tremor , irritability, excitement, tinnitus . Autonomic: sweating ; infrequently flushing; and rarely chills. Allergic: infrequently rash ; and rarely urticaria , edema of the face. Cardiovascular : infrequently decrease in blood pressure , tachycardia . Hematologic: rarely depression of white blood cells (especially granulocytes), which is usually reversible, moderate transient eosinophilia . Other: rarely respiratory depression, urinary retention, paresthesia , serious skin reactions, including erythema multiforme , Stevens-Johnson Syndrome , toxic epidermal necrolysis, and in one instance, an apparent anaphylactic reaction has been reported.
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