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tacrolimus: Drugs Search Results from the Invisible Web

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:: Overview :: Precautions :: Side Effects :: Further Reading Search results last updated: 9/17/2008

Generic & Brand Name : Source: (RXList)

Brand Name : Protopic
Generic Name : Tacrolimus

Overview (Source: MedicineNet)
Tacrolimus is a drug that suppresses the immune system and is used to prevent rejection of transplanted organs. Tacrolimus accomplishes its immune-suppressing effecting by inhibiting an enzyme (calcineurin) crucial for the multiplication of T-cells, cells that are vital to the immune process. The use of oral tacrolimus allows transplantation specialists to reduce the dose of steroids which are also used to prevent rejection. This "steroid-sparing effect" is important because of the many side effects that can occur when larger doses of steroids are used for a long period of time. Tacrolimus was approved by the FDA in April, 1994 for liver transplantation and also has been used in patients for heart, kidney, small bowel, and bone marrow transplantation. ...
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MedLinePlusWhy is this medication prescribed?
DrugDigestWhat is/are Tacrolimus Capsules?
DrugInfoOnlinetacrolimus

Precautions (Source: MedLinePlus)
Before taking tacrolimus, tell your doctor and pharmacist if you are allergic to tacrolimus or any other medications. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: amphotericin B (Abelcet, Ambisome, Amphotec); antacids; certain antibiotics including aminoglycosides such as amikacin, gentamicin, neomycin (Neo-Fradin), streptomycin, and tobramycin (Tobi), and macrolides such as clarithromycin (Biaxin), erythromycin (EES, E-Mycin, Erythrocin), and troleandomycin (TAO) (not available in the US); antifungal medications such as clotrimazole (Lotrimin, Mycelex), fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral) and voriconazole (Vfend); bromocriptine (Parlodel); calcium channel blockers such as diltiazem (Cardizem), nicardipine (Cardene), nifedipine (Adalat, Procardia), and verapamil (Calan, Covera, Isoptin); caspofungin (Cancidas); chloramphenicol; cimetidine (Tagamet); cisapride (Propulsid) (not available in the U.S.); cisplatin (Platinol); danazol (Danocrine); certain diuretics ('water pills'); ganciclovir (Cytovene); hormonal contraceptives (birth control pills, patches, rings, inserts, or injections); HIV protease inhibitors such as indinavir (Crixivan), nelfinavir (Viracept), and ritonavir (Norvir); lansoprazole (Prevacid); certain medications for seizures such as carbamazepine (Tegretol), phenobarbital, ...
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RXList Warnings & Precautions
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Side Effects (Source: MedLinePlus)
Tacrolimus may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: headache; uncontrollable shaking of a part of the body; diarrhea; constipation; nausea; vomiting; heartburn; stomach pain; loss of appetite; difficulty falling asleep or staying asleep; dizziness; weakness; back or joint pain; burning, numbness, pain, or tingling in the hands or feet; rash; itching. Some side effects can be serious. If you experience any of the following symptoms, or those mentioned in the IMPORTANT WARNING section, call your doctor immediately: decreased urination; pain or burning on urination; swelling of the arms, hands, feet, ankles, or lower legs; weight gain; unusual bleeding or bruising; seizures; coma (loss of consciousness for a period of time). Tacrolimus may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html ] or by phone [1-800-332-1088]. ...
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RXList Side Effects & Drug Interactions
DrugDigest What side effects may I notice from this medicine?
DrugInfoOnline tacrolimus

Further Reading on tacrolimus
  • Atopic Dermatitis - Treatment Overview ( WebMD )
    Although there is no cure for atopic dermatitis , it can be controlled with preventive measures and ...applied directly to the skin. Calcineurin inhibitors (pimecrolimus and tacrolimus ) are topical...
  • Kidney transplant ( WebMD )
    A kidney transplant is surgery to replace your own diseased kidneys with a healthy (donor) kidney...system (immunosuppressive medications), such as prednisone, azathioprine, tacrolimus , and...
  • Uric Acid in Blood ( WebMD )
    The blood uric acid test measures the amount of uric acid in a blood sample . Uric acid is produced ...mg daily), niacin, warfarin (such as Coumadin), cyclosporine, levodopa, tacrolimus , and some...

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