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:: Overview :: Precautions :: Side Effects :: Further Reading Search results last updated: 9/17/2008

Generic & Brand Name : Source: (RXList)

Brand Name : Cognex
Generic Name : Tacrine

Overview (Source: MedicineNet)
Tacrine is an oral medication used to treat patients with Alzheimer's disease. Tacrine is in a class of drugs called cholinesterase inhibitors that also includes rivastigmine (Exelon), donepezil (Aricept), and galantamine (Razadyne - formerly known as Reminyl). Cholinesterase inhibitors inhibit (block) the action of acetylcholinesterase, the enzyme responsible for the destruction of acetylcholine. Acetylcholine is one of several neurotransmitters in the brain, chemicals that nerve cells use to communicate with one another. Reduced levels of acetylcholine in the brain are believed to be responsible for some of the symptoms of Alzheimer's disease. By blocking the enzyme that destroys acetylcholine, rivastigmine increases the concentration of acetylcholine in the brain, and this increase is believed to be responsible for the improvement in thinking seen with tacrine. Tacrine was approved by the FDA in 1993. ...
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DrugDigestWhat is/are Tacrine?
MedLinePlusWhy is this medication prescribed?
DrugInfoOnlinetacrine

Precautions (Source: MedLinePlus)
Before taking tacrine, tell your doctor and pharmacist if you are allergic to tacrine or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially atropine-like drugs (belladonna, dicyclomine, and scopolamine); bethanechol; cimetidine (Tagamet); cold, sinus, and allergy medications; fluvoxamine (Luvox); neostigmine; nonsteroidal anti-inflammatory medicine such as aspirin, ibuprofen (Advil, Motrin, or Nuprin), indomethacin (Indocin), and naproxen (Naprosyn); theophylline (Theo-Dur); ulcer medications; and vitamins. tell your doctor if you have or have ever had ulcers; seizures; problems with your urinary system; asthma; or blood vessel, heart, kidney, liver, lung, or stomach disease. Also tell your doctor if you have experienced yellowing of the skin or eyes when you took tacrine in the past. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking tacrine, call your doctor. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking tacrine. you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you. remember that alcohol can add to the drowsiness caused by this drug. ...
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Side Effects (Source: MedLinePlus)
Tacrine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: upset stomach; vomiting; diarrhea; loss of balance; heartburn; muscle aches; headache; loss of appetite. If you experience any of the following symptoms, call your doctor immediately: rash; yellowing of the skin or eyes; changes in stool color; stomach pain; difficulty urinating. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html ] or by phone [1-800-332-1088]. ...
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DrugDigest What side effects may I notice from this medicine?
RXList Side Effects & Drug Interactions
DrugInfoOnline tacrine

Further Reading on tacrine
  • Dementia With Lewy Bodies ( WebMD )
    Dementia with Lewy bodies ( DLB ) is the name for a group of disorders in which dementia , a progressive decline of mental and ...improve memory. Examples include donepezil (Aricept), tacrine (Cognex),

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