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:: Overview :: Precautions :: Side Effects :: Further Reading Search results last updated: 9/16/2008

Generic & Brand Name : Source: (MedicineNet)

Brand Name : Paxil, Paxil CR
Generic Name : paroxetine

Overview (Source: MedicineNet)
Paroxetine is an anti-depressantdrug that affects the chemicals that nerves in the brain use tocommunicate with one another. These chemical messengers, called neurotransmitters, are released by one nerve and taken up by other nerves. Neurotransmitters that are released but not taken up by other nerves are taken up by the nerves that release them ("reuptake"). Many experts believe that it is an imbalance among the amounts of the different neurotransmitters that are released that causes depression . Paroxetine works by inhibiting the reuptake of serotonin by the nerves that release it, an action which allows more serotonin to be available to be taken up by other nerves. Paroxetine is in a class of drugs called selective serotonin reuptake inhibitors (SSRIs), a class that also contains fluoxetine (Prozac) and sertraline (Zoloft). ...
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MedLinePlusWhy is this medication prescribed?
DrugDigestWhat is/are Paroxetine Extended-Release Tablets?

Precautions (Source: MedLinePlus)
Before taking paroxetine, tell your doctor and pharmacist if you are allergic to paroxetine or any other medications. tell your doctor if you are taking monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or have stopped taking them within the past 2 weeks, or if you are taking thioridazine or pimozide (Orap). Your doctor will probably tell you not to take paroxetine. If you stop taking paroxetine, you should wait at least 2 weeks before you start to take an MAO inhibitor. tell your doctor and pharmacist what other prescription and nonprescription medications, and vitamins you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); antidepressants (mood elevators) such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); antihistamines; aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin), and naproxen (Aleve, Naprosyn); atomoxetine (Straterra), atazanavir (Reyataz); bromocriptine (Parlodel); bupropion (Wellbutrin); buspirone (Buspar); celecoxib (Celebrex); chlorpromazine (Thorazine); cimetidine (Tagamet); clopidogrel (Plavix); codeine (found in many c ...
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DrugDigest What should I watch for while using this medicine?

Side Effects (Source: MedLinePlus)
Paroxetine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: headache; dizziness; weakness; difficulty concentrating; nervousness; forgetfulness; confusion; sleepiness or feeling "drugged"; nausea; vomiting; diarrhea; constipation; gas; stomach pain; heartburn; changes in ability to taste food; decreased appetite; weight loss or gain; changes in sex drive or ability; dry mouth; sweating; yawning; sensitivity to light; runny nose; cough; lump or tightness in throat; pain in the back, muscles, joints, or anywhere in the body; muscle weakness or tightness; flushing; problems with teeth; unusual dreams; painful or irregular menstruation. Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately: blurred vision; rapid, pounding, or irregular heartbeat; chest pain; seizure; abnormal bleeding or bruising; sore throat, fever, chills, and other signs of infection; uncontrollable shaking of a part of the body; sudden muscle twitching or jerking that you cannot control; numbness or tingling in your hands, feet, arms, or legs; difficult, frequent, or painful urination; swelling, itching, burning, or infection in the vagina; painful erection that lasts for hours; sudden upset stomach, vomiting, weakness, cramping, bloating, swelling, tightness in hands and feet, dizziness, headache and/or confusion; hives; skin rash; itching; swelling o ...
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Further Reading on paroxetine
  • Premature Ejaculation - Topic Overview ( WebMD )
    What is premature ejaculation ? Premature ejaculation is uncontrolled ejaculation either before or shortly after sexual penetration ,...inhibitors (SSRIs), such as fluoxetine (Prozac), paroxetine ( Paxil ),
  • Postpartum Depression - Treatment Overview ( WebMD )
    The sooner treatment starts for postpartum depression , the better . Learn about postpartum depression ...10 There have been reports of side effects in babies exposed to paroxetine ( Paxil ), fluoxetine...
  • Seasonal Affective Disorder (SAD) - Treatment Overview ( WebMD )
    Treatment for seasonal affective disorder ( SAD ) doesn ' t cure the seasonal depression , but it can help relieve your symptoms . Light ...citalopram (Celexa), fluoxetine (such as Prozac), paroxetine ...
  • Irritable Bowel Syndrome (IBS) Guide - Treatment Overview ( WebMD )
    Treatment for Irritable Bowel Syndrome depends on the severity of the symptoms . Learn more about ...antidepressants such as amitriptyline, or antianxiety agents such as paroxetine ( Paxil ). If stress...
  • REM Sleep Behavior Disorder ( WebMD )
    In a person with REM sleep behavior disorder ( RBD ), the paralysis that normally occurs during REM ...or serotonin reuptake inhibitor use (such as fluoxetine, sertraline, or paroxetine ) or other types...



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