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:: Precautions :: Side Effects :: Further Reading Search results last updated: 9/16/2008

Generic & Brand Name : Source: (RXList)

Brand Name : Taxol
Generic Name : Paclitaxel

Precautions (Source: MedLinePlus)
Before taking paclitaxel, tell your doctor and pharmacist if you are allergic to paclitaxel, cyclosporine (Neoral, Sandimmune), teniposide (Vumon), other drugs containing Cremophor EL (polyoxyethylated castor oil) or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially aspirin and vitamins. tell your doctor if you have or have ever had heart or liver disease. you should know that paclitaxel may interfere with the normal menstrual cycle (period) in women and may stop sperm production in men. However, you should not assume that you cannot get pregnant or that you cannot get someone else pregnant. Women who are pregnant or breast-feeding should tell their doctors before they begin taking this drug. You should not plan to have children while receiving chemotherapy or for a while after treatments. (Talk to your doctor for further details.) Use a reliable method of birth control to prevent pregnancy. Paclitaxel may harm the fetus. do not have any vaccinations (e.g., measles or flu shots) without talking to your doctor. your doctor will prescribe a medication called dexamethasone (Decadron) which must be taken before your treatment. If you forget to take the dexamethasone, tell your doctor as soon as possible. ...
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Side Effects (Source: MedLinePlus)
Side effects from paclitaxel are common, and include: nausea and vomiting; loss of appetite; change in taste; thinned or brittle hair; pain in the joints of the arms or legs lasting 2-3 days; changes in the color of the nails; tingling in the hands or toes. Tell your doctor if either of these symptoms is severe or lasts for several hours: mouth blistering; fatigue. If you experience any of the following symptoms, call your doctor immediately: unusual bruising or bleeding; pain, redness, or swelling at the injection site; change in normal bowel habits for more than 2 days; fever; chills; cough; sore throat; difficulty swallowing; dizziness; shortness of breath; severe exhaustion; skin rash; facial flushing; chest pain. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/report.htm ] or by phone [1-800-332-1088]. ...
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Further Reading on paclitaxel
  • Ovarian Cancer Guide - Treatment Overview ( WebMD )
    Learn about complementary therapy to help with ovarian cancer treatment...for most women. The current standard of treatment is 6 cycles of paclitaxel (Taxol) and carboplatin or cisplatin. Each...
  • Small Cell Lung Cancer Treatment (PDQ®) - Extensive-Stage Small Cell Lung Cancer ( WebMD )
    Note : Some citations in the text of this section are followed by a level of evidence . The PDQ editorial boards use a formal ...etoposide.[23] PET: cisplatin plus etoposide plus paclitaxel .[36]...
  • Esophageal Cancer Treatment (PDQ®) - Treatment Option Overview ( WebMD )
    Note : Some citations in the text of this section are followed by a level of evidence . The PDQ editorial boards use a formal ...0113 and RTOG-0246) trials, for example, containing paclitaxel with or...
  • Non-Small Cell Lung Cancer Treatment (PDQ®) - Treatment Option Overview ( WebMD )
    In non - small cell lung cancer ( NSCLC ), results of standard treatment are poor except for the most localized cancers . All newly ...Several agents, including cisplatin, carboplatin, paclitaxel (Taxol),
  • Small-Cell Lung Cancer ( WebMD )
    Information on Small - Cell Lung Cancer , which accounts for approximately 20 - 25 % of all cases of lung ...cells by inhibiting the duplication of DNA. It is an IV medication. Paclitaxel (Taxol) interferes...


  • Non-Small-Cell Lung Cancer ( WebMD )
    Non – small - cell lung cancer ( NSCLC ) is a catchall term for the 75 % of all lung cancers that are not small - cell type ; they are ...tumor cell growth by interfering with cell division. Paclitaxel (Taxol):...
  • Ovarian Cancer ( WebMD )
    Ovarian Cancer occurs when a tumor forms in one or both of a woman's ovaries...The best treatment at this time involves a platinum-based agent (carboplatin) and paclitaxel (Taxol). These agents are...

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