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:: Overview :: Precautions :: Side Effects :: Further Reading Search results last updated: 9/15/2008

Generic & Brand Name : Source: (MedicineNet)

Brand Name : Synarel
Generic Name : nafarelin

Overview (Source: MedicineNet)
Nafarelin is a synthetic protein chemically similar to the natural gonadotropin-releasing hormone (GnRH), a hormone that regulates the output of gonadotropins by the pituitary gland (a small gland located at the base of the brain). Gonadotropins (FSH and LH) are hormones necessary for estrogen production by the ovaries. When nafarelin (known scientifically as a GnRH analog) is administered continuously to a women in her reproductive years, the pituitary output of FSH and LH, along with the ovary output of estrogen are suppressed. Suppression of estrogen production causes menstruation to stop, resulting in a temporary (but reversible) state of " menopause ". This temporary menopause is important in shrinking endometriosis tissue and in relieving pain of endometriosis. ...
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MedLinePlusWhy is this medication prescribed?
DrugDigestWhat is/are Nafarelin Acetate Nasal Spray?
DrugInfoOnlinenafarelin

Precautions (Source: MedLinePlus)
Before using nafarelin, tell your doctor and pharmacist if you are allergic to nafarelin, gonadotropin-releasing hormones, or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially anticonvulsants to treat seizures or epilepsy, nasal decongestants, steroids, and vitamins. tell your doctor if you have or have ever had osteoporosis or a family history of osteoporosis; ovarian cysts, ovarian tumors, or ovarian cancer; chronic rhinitis (runny nose); or a history of depression. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. It is important to use a non-hormonal means of contraception (birth control) while using nafarelin (e.g., condom or diaphragm). If you become pregnant while using nafarelin, call your doctor immediately. ...
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DrugDigest What should I watch for while using this medicine?

Side Effects (Source: MedLinePlus)
Nafarelin may cause side effects. Usually these symptoms are temporary, lasting only until your body adjusts to the medication. Tell your doctor if any of these symptoms are severe or do not go away: acne; breast enlargement; vaginal bleeding (menstruation should stop with this medication); mood swings; increase in pubic hair; body odor; seborrhea (skin irritation); nasal irritation; headache; hot flashes; insomnia; change in weight; vaginal dryness or vaginal discharge; change in sex drive; oily skin; muscle aches; rhinitis (runny nose); depression. If you experience any of the following symptoms, call your doctor immediately: stomach pain not related to menstruation; shortness of breath or difficulty breathing; chest pain; rash; severe itching. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html ] or by phone [1-800-332-1088]. ...
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DrugInfoOnline nafarelin

Further Reading on nafarelin

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