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:: Overview :: Precautions :: Side Effects :: Further Reading Search results last updated: 9/14/2008

Generic & Brand Name : Source: (RXList)

Brand Name : Femara
Generic Name : Letrozole

Overview (Source: MedicineNet)
Letrozole is an oral, anti-estrogen drug that is used for treating postmenopausal women with breast cancer . The growth of some breast cancers in postmenopausal women is promoted by estrogens that circulate in the blood, and the adrenal glands are the main source of these circulating estrogens. Letrozole inhibits the enzyme in the adrenal glands (aromatase) that produces the estrogens, estradiol and estrone. Letrozole was approved by the FDA in 1997. ...
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Precautions (Source: MedLinePlus)
Before taking letrozole, tell your doctor and pharmacist if you are allergic to letrozole, any other medications, or any of the inactive ingredients in letrozole tablets. Ask your doctor or pharmacist for a list of the inactive ingredients. tell your doctor or pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements and herbal products you are taking or plan to take. Be sure to mention any of the following: other medications to treat cancer, medications that contain estrogen such as hormone replacement therapy and hormonal contraceptives (birth control pills, patches, rings, and injections), tamoxifen (Nolvadex), and raloxifene (Evista). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had any medical condition, especially liver disease and osteoporosis (condition in which the bones are weak and break easily). you should know that letrozole should only be used by women who have experienced menopause and cannot become pregnant. However, if you are pregnant or breastfeeding, you should tell your doctor before you begin taking this medication. Use a reliable method of birth control to prevent pregnancy during your treatment. Letrozole may harm the fetus. you should know that letrozole may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you. ...
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Side Effects (Source: MedLinePlus)
Letrozole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: hot flushes; night sweats; nausea; vomiting; muscle, joint, or bone pain; excessive tiredness; headache; dizziness; muscle weakness; swelling of the hands, feet, ankles, or lower legs; loss of appetite; constipation; diarrhea; stomach pain; difficulty falling asleep or staying asleep; vaginal bleeding or irritation; breast pain; flu-like symptoms; difficulty urinating; pain on urination; cough; rash. Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately: chest pain; difficulty breathing. Letrozole may cause or worsen osteoporosis. Talk to your doctor about the risk of taking this medication and to find out what you can do to decrease this risk. Letrozole may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication. ...
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Further Reading on femara
  • Breast Cancer - Treatment Overview ( WebMD )
    Breast cancer is usually treated with surgery, medications, and radiation therapy...body. Medicine such as an aromatase inhibitor (such as Arimidex, Aromasin, or Femara ), or tamoxifen (Nolvadex) may...
  • Breast Cancer Prevention (PDQ®) - Description of Evidence ( WebMD )
    Screening for breast cancer decreases mortality by identifying and treating cases at an earlier ...production in postmenopausal women. Anastrozole (Arimidex) and letrozole ( Femara ) inhibit aromatase...
  • Sexless Marriage ( WebMD )
    ...hotmail.com Tamoxifen killed my desire for sex. After numerous other miserable side effects for almost 3 years, I was finally changed to letrozole/ femara and unfortunately, still no sexual desire.
  • Hormone Therapy for Breast Cancer Treatment ( WebMD )
    An introduction to hormone therapy as a breast cancer treatment...are several common hormone therapy drugs used for breast cancer: Tamoxifen Fareston Arimidex Aromasin Femara Zoladex Tamoxifen (marketed...

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