In controlled clinical trials , the most frequent adverse reactions reported to be related to Dovonex Scalp Solution, 0.005%, use were transient burning, stinging and tingling, which occurred in approximately 23% of patients. Rash was reported in about 11% of patients. Dry skin , irritation and worsening of psoriasis was reported in 1-5% of patients. Skin atrophy , hyperpigmentation , hypercalcemia , and folliculitis were not observed in these studies, but cannot be excluded.
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